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Human infectious diseases may be characterized by their case fatality rate (CFR), the proportion of people diagnosed with a disease who die from it (cf. mortality rate).It should not be confused with the infection fatality rate (IFR), the estimated proportion of people infected by a disease-causing agent, including asymptomatic and undiagnosed infections, who die from the disease.
The yardstick for human mortality from H5N1 is the case-fatality rate (CFR); the ratio of the number of confirmed human deaths resulting from infection of H5N1 to the number of those confirmed cases of infection with the virus. For example, if there are 100 confirmed cases of a disease and 50 die as a consequence, then the CFR is 50%.
Between 2003 and November 2024, the World Health Organization has recorded 948 cases of confirmed H5N1 influenza, leading to 464 deaths. [6] The true fatality rate may be lower because some cases with mild symptoms may not have been identified as H5N1. [7]
Since 2003, 954 confirmed cases of human H5N1 have been reported to the World Health Organization, and about half of those people have died. The case fatality rate is approximately 52%, per the CDC .
The Global Burden of Disease Study began in 1990 as a single World Bank–commissioned [3] study that quantified the health effects of more than 100 diseases and injuries for eight regions of the world, giving estimates of morbidity and mortality by age, sex, and region.
[19] [20] [21] The morbidity and mortality of TB and HIV/AIDS have been closely linked, known as "TB/HIV syndemic". [21] [22] According to the World Health Organization, approximately 10 million new TB infections occur every year, and 1.5 million people die from it each year – making it the world's top infectious killer (before COVID-19 ...
Influenza mortality in symptomatic cases in the US for the 2018/2019 season [66] Influenza is typically characterized by seasonal epidemics and sporadic pandemics. Most of the burden of influenza is a result of flu seasons caused by influenza A virus and influenza B virus.
The following is a list of the causes of human deaths worldwide for different years arranged by their associated mortality rates. In 2002, there were about 57 million deaths. In 2005, according to the World Health Organization (WHO) using the International Classification of Diseases (ICD), about 58 million people died. [1]