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Cerebral edema is commonly seen in a variety of brain injuries including ischemic stroke, subarachnoid hemorrhage, traumatic brain injury, subdural, epidural, or intracerebral hematoma, hydrocephalus, brain cancer, brain infections, low blood sodium levels, high altitude, and acute liver failure.
High levels of intracellular Ca 2+, the major cause of post-injury cell damage, [30] destroy mitochondria, [11] and trigger phospholipases and proteolytic enzymes that damage Na+ channels and degrade or alter the cytoskeleton and the axoplasm. [31] [26] Excess Ca 2+ can also lead to damage to the blood–brain barrier and swelling of the brain ...
Although it is a diffuse type of brain injury itself, diffuse vascular injury is generally more likely to be caused by focal than diffuse injury. [4] Swelling, commonly seen after TBI, can lead to dangerous increases in intracranial pressure. [4] Though swelling itself is a diffuse type of injury, it can result from either focal or diffuse ...
Epidural hematoma is usually found on the same side of the brain which was impacted by the blow, but on very rare occasions it can be due to a contrecoup injury. [ 12 ] A "heat hematoma" is an epidural hematoma caused by severe thermal burn , causing contraction and exfoliation of the dura mater and exfoliate from the skull, in turn causing ...
A traumatic brain injury (TBI), also known as an intracranial injury, is an injury to the brain caused by an external force. TBI can be classified based on severity ranging from mild traumatic brain injury (mTBI/concussion) to severe traumatic brain injury. [ 5 ]
More than 50% of patients who suffer from a traumatic brain injury will develop psychiatric disturbances. [6] Although precise rates of anxiety after brain injury are unknown, a 30-year follow-up study of 60 patients found 8.3% of patients developed a panic disorder, 1.7% developed an anxiety disorder, and 8.3% developed a specific phobia. [7]
Lee's death was officially ruled the result of cerebral edema — swelling of the brain. While a normal human brain is about 3 pounds, Lee's was reportedly closer to 3½ pounds.
An increase in pressure, most commonly due to head injury leading to intracranial hematoma or cerebral edema, can crush brain tissue, shift brain structures, contribute to hydrocephalus, cause brain herniation, and restrict blood supply to the brain. [13] It is a cause of reflex bradycardia. [14]