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Sézary disease, or Sézary syndrome, [1] is a type of cutaneous T-cell lymphoma that was first described by Albert Sézary. [2] The affected T cells , known as Sézary's cells or Lutzner cells , have pathological quantities of mucopolysaccharides .
Cutaneous T-cell lymphoma (CTCL) is a class of non-Hodgkin lymphoma, which is a type of cancer of the immune system.Unlike most non-Hodgkin lymphomas (which are generally B-cell-related), CTCL is caused by a mutation of T cells.
The CMA has over 75,000 members [2] and is the largest association of medical doctors in Canada. Its membership includes physicians and medical learners. The CMA represents Canadian physicians from medical school through to residency, medical practice and retirement.
In Lutzner cells, there is a mutation in the T-cell receptor that inhibits antigens like CD8 and CD7, but stimulates the over production of other antigens like CD4. This mutation is a clonal gene rearrangement at the TCR-γ gene. Clonal gene rearrangements create novel or new surface antibodies during early differentiation. [2]
"Article 2 (Definition): "Disabled persons" as used in this Law means persons whose daily life or life in society is substantially limited over the long term due to a physical disability, mental retardation or mental disability. Article 3 (Fundamental Principles): The dignity of all disabled persons shall be respected.
The Canada Health Act covers the services of psychiatrists, medical doctors with additional training in psychiatry. In Canada, psychiatrists tend to focus on the treatment of mental illness with medication. [67] However, the Canada Health Act excludes care provided in a "hospital or institution primarily for the mentally disordered."
The Niagara Health System, or Niagara Health (NH), is a Canadian multi-site hospital amalgamation, comprising five sites serving over 450,000 residents across the 12 municipalities making up the Regional Municipality of Niagara, Canada. Niagara Health is one of Ontario's largest hospital systems, with 4,800 employees, 600 physicians and 850 ...
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