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Hydroxyproline is a major component of the protein collagen, [3] comprising roughly 13.5% of mammalian collagen. Hydroxyproline and proline play key roles for collagen stability. [4] They permit the sharp twisting of the collagen helix. [5]
Collagen is also abundant in corneas, blood vessels, the gut, intervertebral discs, and the dentin in teeth. [3] In muscle tissue, it serves as a major component of the endomysium. Collagen constitutes 1% to 2% of muscle tissue and accounts for 6% of the weight to skeletal muscle. [4] The fibroblast is the most common cell creating collagen in ...
Gout, called podagra in ancient Greek medicine, is a common arthritis caused by deposition of monosodium urate crystals within the joints. [9] Gout usually affects the first metatarsophalangeal joint of the big toe and later the other joints of the feet and hands.
The same cannot be said for human bone collagen, as δ 18 O values in collagen seem to be impacted by drinking water, food water, and a combination of metabolic and physiological processes. [ 84 ] δ 18 O values from bone minerals are essentially an averaged isotopic signature throughout the entire life of the individual.
Connective tissue disease, also known as connective tissue disorder, or collagen vascular diseases, refers to any disorder that affects the connective tissue. [1] The body's structures are held together by connective tissues, consisting of two distinct proteins : elastin and collagen .
Vitamin C, for example, aids in the collagen synthesis process, keeping skin firm and plump. Zinc is helpful for making keratin, the protein found in hair and nails. Copper helps the body process ...
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