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They inhibit release of thyroid hormones by the thyroid gland.The most studied drug in this class is lithium, which inhibits thyroid hormone secretion by inhibiting iodotyrosine coupling, thyroidal iodide uptake, and alteration in structure of thyroglobulin, [10] a protein which acts as a substrate for the synthesis of thyroid hormones and storage of inactive forms of T3, T4 and iodine within ...
Pages in category "Antithyroid drugs" The following 8 pages are in this category, out of 8 total. This list may not reflect recent changes. A. Amphenone B;
Furthermore, reviewing their medications and possible dietary supplements is important, as several medications can affect thyroid hormone levels. [14] Levothyroxine is also used to treat subclinical hypothyroidism, which is defined by an elevated TSH level and a normal-range free T 4 level without symptoms. [14]
Propylthiouracil is in the antithyroid family of medications. [4] It works by decreasing the amount of thyroid hormone produced by the thyroid gland and blocking the conversion of thyroxine (T4) to triiodothyronine (T3). [3] Propylthiouracil came into medical use in the 1940s. [5] It is on the World Health Organization's List of Essential ...
Levothyroxine, a drug used to treat hypothyroidism, can lead to reduced bone mass and density in older adults with normal thyroid levels, a small cohort study has shown.
Thioamides or anti-thyroid drugs are also a class of drugs that are used to control thyrotoxicosis. Thioamides have been incorporated into peptides as isosteres for the amide bond. [ 10 ] Peptide modifications are analogues of the native peptide, which can reveal the structure-activity relationship ( SAR ).