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Migraines in middle-aged women are primarily related to fluctuations in hormone levels; perimenopause causes a decline in estrogen, which triggers these very specific types of headaches in ...
Estrogen deficiency is also associated with an increased risk of cardiovascular disease, [1] and has been linked to diseases like urinary tract infections [2] and osteoporosis. In women, low levels of estrogen may cause symptoms such as hot flashes, sleeping disturbances, decreased bone health, [3] and changes in the genitourinary system.
Changes in sexual health: Lower estrogen levels can lead to low libido, more trouble achieving orgasm and vaginal dryness, which can cause burning and pain during sex, Tang says. Many women find ...
Pain in women. Migraines are more likely to strike women than men. Roughly one in five women is thought to suffer from these potentially debilitating headaches, compared with fewer than one in 10 men.
Estrogen can also reduce vaginal atrophy and increase sexual arousal, frequency and orgasm. [22] The effectiveness of hormone replacement can decline in some women after long-term use. [22] A number of studies have also found that the combined effects of estrogen/androgen replacement therapy can increase libido and arousal over estrogen alone. [22]
Estrogen insensitivity syndrome (EIS), or estrogen resistance, is a form of congenital estrogen deficiency or hypoestrogenism [2] which is caused by a defective estrogen receptor (ER) – specifically, the estrogen receptor alpha (ERα) – that results in an inability of estrogen to mediate its biological effects in the body. [3]
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