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ITP affects the whole patient,
not just their platelets
- Future of ITP
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- Living With ITP
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Pregnant women with ITP are 1.83 times more likely to have bleeding episodes during pregnancy compared to non-pregnant females with ITP, however, with proper treatment, platelets rarely drop below 30,000. [63] In ITP, severe bleeding is a rare occurrence, and with treatment maternal deaths due to ITP are extremely rare. [63]
Rituximab, sold under the brand name Rituxan among others, is a monoclonal antibody medication used to treat certain autoimmune diseases and types of cancer. [18] It is used for non-Hodgkin lymphoma, chronic lymphocytic leukemia (in children and adults, but not recommended in elderly patients), rheumatoid arthritis, granulomatosis with polyangiitis, idiopathic thrombocytopenic purpura ...
This regimen can also be combined with the monoclonal antibody rituximab if the lymphoma is of B cell origin; this combination is called R-CHOP. In 2002, a randomized controlled trial showed a higher complete response rate for R-CHOP vs CHOP in elderly patients with Diffuse Large-B-Cell Lymphoma (76% vs 63%). [4]
Thrombotic thrombocytopenic purpura (TTP) is a blood disorder that results in blood clots forming in small blood vessels throughout the body. [2] This results in a low platelet count, low red blood cells due to their breakdown, and often kidney, heart, and brain dysfunction. [1]
The incident began Saturday around 4:30 p.m. local time when a police officer detected an unmanned aircraft system operating "dangerously close" to Logan International Airport, the statement said.
While the immune pathogenesis is ultimately demonstrated in many patients and early treatment is usually via immunosuppressants (e.g., prednisone, rituximab, etc.), immunosuppression is not a viable long-term treatment due to the cummulative (and sometimes fatal) side-effects of the pharmaceuticals involved, as well as the obvious problem of ...
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