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When viewed under a microscope, the bladder can be seen to have an inner lining (called epithelium), three layers of muscle fibres, and an outer adventitia. [ 8 ] The inner wall of the bladder is called urothelium , a type of transitional epithelium formed by three to six layers of cells; the cells may become more cuboidal or flatter depending ...
The trigone (also known as the vesical trigone) [1] is a smooth triangular region of the internal urinary bladder formed by the two ureteric orifices and the internal urethral orifice. The area is very sensitive to expansion and once stretched to a certain degree, stretch receptors in the urinary bladder signal the brain of its need to empty ...
The ureter is surrounded by two muscular layers, an inner longitudinal layer of muscle, and an outer circular or spiral layer of muscle. [6] [7] The lower third of the ureter has a third muscular layer. [7] Beyond these layers sits an adventitia containing blood vessels, lymphatic vessels, and veins. [7]
Should the transitional cell carcinoma grow toward the inner surface of the bladder via finger-like projections, it is known as papillary carcinoma. Otherwise, it is known as flat carcinoma. [11] Either form can transition from non-invasive to invasive by spreading into the muscle layers of the bladder.
Bowman's space (or "urinary space", or "capsular space")—Between the visceral and parietal layers, into which the filtrate enters after passing through the filtration slits. [1] Visceral layer—Lies just above the thickened glomerular basement membrane and is made of podocytes. Beneath the visceral layer lie the glomerular capillaries.
The anatomy of the human urinary system differs between males and females at the level of the urinary bladder. In males, the urethra begins at the internal urethral orifice in the trigone of the bladder, continues through the external urethral orifice, and then becomes the prostatic, membranous, bulbar, and penile urethra.
Since then many discoveries have been made. Nephrotic syndrome occurs when there is a breakdown of the glomerular filtration barrier. The podocytes form one layer of the filtration barrier. Genetic mutations can cause podocyte dysfunction leading to an inability of the filtration barrier to restrict urinary protein loss.
The front is known as the "vesical layer". It forms the anterior and lateral ligaments of the bladder. In males, its middle lamina crosses the floor of the pelvis between the rectum and vesiculæ seminales as the rectovesical septum; in the female this is perforated by the cervix and is named the transverse cervical ligament.