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When viewed under a microscope, the bladder can be seen to have an inner lining (called epithelium), three layers of muscle fibres, and an outer adventitia. [ 8 ] The inner wall of the bladder is called urothelium , a type of transitional epithelium formed by three to six layers of cells; the cells may become more cuboidal or flatter depending ...
The trigone (also known as the vesical trigone) [1] is a smooth triangular region of the internal urinary bladder formed by the two ureteric orifices and the internal urethral orifice. The area is very sensitive to expansion and once stretched to a certain degree, stretch receptors in the urinary bladder signal the brain of its need to empty ...
The front is known as the "vesical layer". It forms the anterior and lateral ligaments of the bladder. In males, its middle lamina crosses the floor of the pelvis between the rectum and vesiculæ seminales as the rectovesical septum; in the female this is perforated by the cervix and is named the transverse cervical ligament.
Weak pelvic floor muscles, intrinsic sphincter damage, or damage to the surrounding nerves and tissue can make the urethral sphincter incompetent, and subsequently it will not close fully, leading to stress urinary incontinence. In women, childbirth, obesity, and age can all be risk factors, especially by weakening the pelvic floor muscles. [6]
The bladder also contains β 3 adrenergic receptors, and pharmacological agonists of this receptor are used to treat overactive bladder. The mucosa of the urinary bladder may herniate through the detrusor muscle. [6] This is most often an acquired condition due to high pressure in the urinary bladder, damage, or existing connective tissue ...
The pelvic floor or pelvic diaphragm is an anatomical location in the human body, [1] which has an important role in urinary and anal continence, sexual function and support of the pelvic organs. [2] The pelvic floor includes muscles, both skeletal and smooth, ligaments and fascia.
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The internal urethral sphincter is a urethral sphincter muscle which constricts the internal urethral orifice.It is located at the junction of the urethra with the urinary bladder and is continuous with the detrusor muscle, [1] [2] but anatomically and functionally fully independent from it. [3]