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Alpha-1 blocker. Alpha-1 blockers (also called alpha-adrenergic blocking agents or alpha-1 antagonists) constitute a variety of drugs that block the effect of catecholamines on alpha-1-adrenergic receptors. They are mainly used to treat benign prostatic hyperplasia (BPH), hypertension and post-traumatic stress disorder. [1]
Alpha-blockers, also known as α-blockers or α-adrenoreceptor antagonists, are a class of pharmacological agents that act as antagonists on α-adrenergic receptors (α-adrenoceptors). [2] Historically, alpha-blockers were used as a tool for pharmacologic research to develop a greater understanding of the autonomic nervous system.
Tamsulosin. Tamsulosin, sold under the brand name Flomax among others, is a medication used to treat symptomatic benign prostatic hyperplasia (BPH) and chronic prostatitis and to help with the passage of kidney stones. [6][7][8] The evidence for benefit with a kidney stone is better when the stone is larger. [8] Tamsulosin is taken by mouth. [6]
Alfuzosin, sold under the brand name Uroxatral among others, is a medication of the α 1 blocker class. It is used to treat benign prostatic hyperplasia (BPH). [1]As an antagonist of the α 1 adrenergic receptor, it works by relaxing the muscles in the prostate and bladder neck, making urination easier.
Heart failure may be worsened with nondihydropyridine calcium channel blockers, the alpha blocker doxazosin, and the alpha-2 agonists moxonidine and clonidine. On the other hand, β-blockers, diuretics, ACE inhibitors, angiotensin receptor blockers, and aldosterone receptor antagonists have been shown to improve outcome. [67] Pregnancy ...
It was the first alpha blocker which was used for treating Benign Prostatic Hyperplasia. [22] Another Alpha Blocker Prazosin, which was the first drug selective to alpha 1 receptor, was developed in 1987 [22] for the therapy of Benign Prostatic Hyperplasia. Other alpha blockers are then introduced for several diseases. [22]
Silodosin, sold under the brand name Urief among others, is a medication for the symptomatic treatment of benign prostatic hyperplasia. [4][5] It acts as an alpha-1 adrenergic receptor antagonist. [4][5] The most common side effect is a reduction in the amount of semen released during ejaculation. [5]
Research shows that taking 5 milligrams (mg) of finasteride a day for benign prostatic hyperplasia (BPH) — an enlarged prostate — can lead to a 15 to 25 percent increase in testosterone levels.