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MDI canister and actuator components from H&T Presspart. A metered-dose inhaler consists of three major components: the canister, which is produced in aluminum or stainless steel by means of deep drawing, where the formulation resides; the metering valve, which allows a metered quantity of the formulation to be dispensed with each actuation; and an actuator (or mouthpiece) which enables the ...
This technique is most commonly used in the treatment of lung diseases, for example, asthma and chronic obstructive pulmonary disease (COPD). Different types of inhalers include metered-dose inhalers (MDI), dry powder inhalers (DPI), soft mist inhalers (SMI) and nebulizers. The rate and efficacy of pulmonary drug delivery are affected by drug ...
An inhaler (puffer, asthma pump or allergy spray) is a medical device used for delivering medicines into the lungs through the work of a person's breathing. This allows medicines to be delivered to and absorbed in the lungs, which provides the ability for targeted medical treatment to this specific region of the body, as well as a reduction in the side effects of oral medications.
For children aged under five years they recommend that a spacer (with a face mask if necessary) is used with a metered dose inhaler for administering both inhaled bronchodilators and ...
Recent evidence shows that nebulizers are no more effective than metered-dose inhalers (MDIs) with spacers. [5] An MDI with a spacer may offer advantages to children who have acute asthma. [3] [6] [5] Those findings refer specifically to the treatment of asthma and not to the efficacy of nebulisers generally, as for COPD for example. [5]
Oral corticosteroids began to be used for the condition in 1950. The use of a pressurized metered-dose inhaler was developed in the mid-1950s for the administration of adrenaline and isoproterenol and was later used as a beta 2-adrenergic agonist. Inhaled corticosteroids and selective short-acting beta agonists came into wide use in the 1960s.
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