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140,000 (2021) [ 9 ] Epilepsy is a group of non-communicable neurological disorders characterized by recurrent epileptic seizures. [ 10 ] An epileptic seizure is the clinical manifestation of an abnormal, excessive, and synchronized electrical discharge in the neurons. [ 1 ] The occurrence of two or more unprovoked seizures defines epilepsy. [ 11 ]
Management of drug-resistant epilepsy. Drug-resistant epilepsy (DRE), also known as refractory epilepsy, intractable epilepsy, or pharmacoresistant epilepsy, is diagnosed following a failure of adequate trials of two tolerated and appropriately chosen and used antiepileptic drugs (AEDs) (whether as monotherapies or in combination) to achieve ...
Anticonvulsant. Anticonvulsants (also known as antiepileptic drugs, antiseizure drugs, or anti-seizure medications (ASM)) are a diverse group of pharmacological agents used in the treatment of epileptic seizures. [ 1 ] Anticonvulsants are also increasingly being used in the treatment of bipolar disorder [ 2 ][ 3 ] and borderline personality ...
In seizures related to toxins, up to two doses of benzodiazepines should be used. [83] If this is not effective pyridoxine is recommended. [83] Phenytoin should generally not be used. [83] There is a lack of evidence for preventive anti-epileptic medications in the management of seizures related to intracranial venous thrombosis. [75]
Appropriate medication is the best way to manage absence seizures, but prevention can be considerably enhanced by life-style changes such as exercise, stress reduction, good sleep hygiene, and healthy diet. [35] In particular, a therapeutic ketogenic diet can be very beneficial. In a review of studies of childhood and juvenile patients, this ...
Status epilepticus (SE), or status seizure, is a medical condition consisting of a single seizure lasting more than 5 minutes, or 2 or more seizures within a 5-minute period without the person returning to normal between them. [3][1] Previous definitions used a 30-minute time limit. [2] The seizures can be of the tonic–clonic type, with a ...
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