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Scleroderma is a group of autoimmune diseases that may result in changes to the skin, blood vessels, muscles, and internal organs. [2] [6] [8] The disease can be either localized to the skin or involve other organs, as well. [2]
Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse ...
Morphea is a form of scleroderma that mainly involves isolated patches of hardened skin on the face, hands, and feet, or anywhere else on the body, usually with no internal organ involvement. [1] However, in Deep Morphea inflammation and sclerosis can be found in the deep dermis , panniculus , fascia , superficial muscle and bone.
Skin None specific Uncertain 1-4% [15] Lichen planus: Skin, mucous membranes None specific Probable 1% [16] Lichen sclerosus: Skin None specific Probable Rare [17] Linear IgA disease: Skin Anti-epidermal basement membrane IgA Confirmed Extremely rare [18] Morphea: Skin None specific Probable Not well established [19] Psoriasis: Skin Various ...
People with scleroderma overlap syndrome have symptoms of both systemic scleroderma and/or polymyositis and dermatomyositis: Scleroderma: a group of rare diseases that involve the hardening and tightening of the skin and connective tissues. Polymyositis: a rare inflammatory disease that causes muscle weakness affecting both sides of your body.
Kim Kardashian revealed that one of her sons with ex-husband Kanye West inherited a skin disorder from her. “It came from my mom [and] went to me. And I passed it on in a different form to my ...
The rare disease hardens the skin and internal organs of young women of child-bearing age causing disfigurement, and is potentially fatal. [5] In reaction to the lack of awareness of the disease in the medical community, she went on to found the Scleroderma Research Foundation in 1987, [2] an organization dedicated to finding a cure. [4]
In addition to the skin lesions, chronic liver disease is very common in patients with sporadic PCT. This involves hepatic fibrosis (scarring of the liver), and inflammation. However, liver problems are less common in patients with the inherited form of the disease. [5]
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