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  2. BRCA mutation - Wikipedia

    en.wikipedia.org/wiki/BRCA_mutation

    BRCA 2 has the cytogenetic location 13q12.3 or the q arm of Chromosome 13 at position 12.3. Both genes produce proteins that help repair damaged DNA, keeping the genetic material of the cell stable. A damaged BRCA gene in either location can lead to increased risk of cancer, particularly breast or ovarian in women.

  3. BRCA2 - Wikipedia

    en.wikipedia.org/wiki/BRCA2

    BRCA2 and BRCA2 (/ ˌ b r æ k ə ˈ t uː / [5]) are human genes and their protein products, respectively. The official symbol (BRCA2, italic for the gene, nonitalic for the protein) and the official name (originally breast cancer 2; currently BRCA2, DNA repair associated) are maintained by the HUGO Gene Nomenclature Committee.

  4. BRCA1 - Wikipedia

    en.wikipedia.org/wiki/BRCA1

    Certain variations of the BRCA1 gene lead to an increased risk for breast cancer as part of a hereditary breast–ovarian cancer syndrome. Researchers have identified hundreds of mutations in the BRCA1 gene, many of which are associated with an increased risk of cancer. Females with an abnormal BRCA1 or BRCA2 gene have up to an 80% risk of ...

  5. I have the BRCA1 mutation, and so does 1 of my ... - AOL

    www.aol.com/news/brca1-mutation-does-1-daughters...

    Jen Culton learned she had the BRCA1 gene mutation after her older sister's breast-cancer diagnosis. She decided to have two of her daughters tested; one daughter also has the BRCA1 gene mutation.

  6. Breast and ovarian cancer - Wikipedia

    en.wikipedia.org/wiki/Breast_and_ovarian_cancer

    Mutations in BRCA1 and BRCA2 are 10 times more common in Ashkenazi Jewish individuals. [18] 2.5% of individuals of Ashkenazi Jewish ancestry have such mutations. [14] Genetic testing is available for testing mutations in BRCA1 and BRCA2. Methods include sequence analysis and gene-targeted deletion/duplication analysis. [10]

  7. Can 23andMe Detect the BRCA Gene? What To Know Before ... - AOL

    www.aol.com/news/23andme-detect-brca-gene-know...

    Home genetic test kits from 23andMe may detect some important BRCA gene mutations that can increase your risk for breast cancer. Here's what to know before you test.

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