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The posterior thoracic nucleus, (Clarke's column, column of Clarke, dorsal nucleus, nucleus dorsalis of Clarke) is a group of interneurons found in the medial part of Rexed lamina VII, also known as the intermediate zone, of the spinal cord.
The dorsal column nuclei each have an associated nerve tract in the spinal cord, the gracile fasciculus and the cuneate fasciculus, together forming the dorsal columns. Both dorsal column nuclei contain synapses from afferent nerve fibers that have travelled in the spinal cord. [2] They then send on second-order neurons of the dorsal column ...
Subacute combined degeneration of spinal cord; Diagram of the principal fasciculi of the spinal cord. (In subacute combined degeneration of spinal cord, the "combined" refers to the fact that the dorsal columns and lateral corticospinal tracts are both affected, in contrast to tabes dorsalis which is selective for the dorsal columns.)
The name dorsal-column medial lemniscus comes from the two structures that carry the sensory information: the dorsal columns of the spinal cord, and the medial lemniscus in the brainstem. There are three groupings of neurons that are involved in the pathway: first-order neurons, second-order neurons, and third-order neurons.
A small nerve may consist of a single funiculus, but a larger nerve will have several funiculi collected together into larger bundles known as fascicles. Fascicles are bound together in a common membrane, the epineurium. [1] [2] Funiculi in the spinal cord are columns of white matter. [3] [4] Examples include: Anterior funiculus of the spinal cord
Dorsal column–medial lemniscus pathway. Gracile fasciculus; Cuneate fasciculus; Medial lemniscus; Spinothalamic tract. Lateral spinothalamic tract; Anterior spinothalamic tract; Spinomesencephalic tract; Spinocerebellar tract; Spino-olivary tract; Spinoreticular tract
The posterolateral tract contains centrally projecting axons from dorsal root ganglion cells carrying peripheral pain and temperature information (location, intensity and quality). These axons enter the spinal column and penetrate the grey matter of the dorsal horn, where they synapse on second-order neurons in either the substantia gelatinosa ...
The dorsal column nuclei are responsible for fine touch, vibration, proprioception and two-point discrimination. The fibers of this decussation are called the internal arcuate fibers and are found at the superior aspect of the closed medulla oblongata, superior to the motor decussation. Neurons of these nuclei are second-order neurons in the ...