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In the United States, it is illegal to market products containing ephedrine or ephedra alkaloids as a dietary supplement. [1] In 2004, ephedra, a botanical source of ephedrine alkaloids, was banned by the U.S. Food and Drug Administration due to serious safety concerns, injuries, and deaths linked to ephedra-containing supplements. However ...
Ephedrine works by inducing the release of norepinephrine and hence indirectly activating the α-and β-adrenergic receptors. [11] Chemically, ephedrine is a substituted amphetamine and is the (1R,2S)-enantiomer of β-hydroxy-N-methylamphetamine. [14] Ephedrine was first isolated in 1885 and came into commercial use in 1926.
A wide variety of alkaloid and non-alkaloid compounds have been identified in various species of Ephedra.Of the six ephedrine-type ingredients found in ephedra (at concentrations of 0.02-3.4%), the most common are ephedrine and pseudoephedrine, [13] which are the sources of its stimulant and thermogenic effects. [4]
Top Prescription Weight Loss Pills. Anti-obesity medications (AOMs) date back to the 1940s — well before modern regulations from the FDA (U.S. Food and Drug Administration) (FDA) were in place ...
Kapex is a weight loss supplement specifically formulated to support those on keto and other low-carb diets. The blend of powerful ingredients is designed to optimize digestion, support muscle ...
Metabolife International, Inc. was a multi-level marketing company based in San Diego, California which manufactured dietary supplements.Metabolife's best-selling product, an ephedra supplement called Metabolife 356, once generated hundreds of millions of dollars in annual sales. [1]