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Stromal cells, or mesenchymal stromal cells, are differentiating cells found in abundance within bone marrow but can also be seen all around the body. Stromal cells can become connective tissue cells of any organ , for example in the uterine mucosa ( endometrium ), prostate , bone marrow , lymph node and the ovary .
The stroma of the bone marrow includes all tissue not directly involved in the marrow's primary function of hematopoiesis. [6] Stromal cells may be indirectly involved in hematopoiesis, providing a microenvironment that influences the function and differentiation of hematopoietic cells.
Mesenchymal stem cells (MSCs), also known as mesenchymal stromal cells or medicinal signaling cells, are multipotent stromal cells that can differentiate into a variety of cell types, including osteoblasts (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and adipocytes (fat cells which give rise to marrow adipose tissue).
The cells which make up stroma tissues serve as a matrix in which the other cells are embedded. [2] Stroma is made of various types of stromal cells. Examples of stroma include: stroma of iris; stroma of cornea; stroma of ovary; stroma of thyroid gland; stroma of thymus; stroma of bone marrow; lymph node stromal cell; multipotent stromal cell ...
Tetherin, also known as bone marrow stromal antigen 2, is a lipid raft associated protein that in humans is encoded by the BST2 gene. [5] [6] [7] In addition, tetherin has been designated as CD317 (cluster of differentiation 317). This protein is constitutively expressed in mature B cells, plasma cells and plasmacytoid dendritic cells, and in ...
There are more than 20 types of reticular fibers. In Reticular Connective Tissue type III collagen/reticular fiber (100-150 nm in diameter) is the major fiber component. It forms the architectural framework of liver, adipose tissue, bone marrow, spleen and basement membrane, to name a few.
Furthermore, areolar tissue is the same as loose connective tissue, adipose tissue is a subset of specialized connective tissue, and reticular tissue is the presence of reticular fibers and reticular cells together forming the stroma of hemopoietic tissue (specifically the red bone marrow) and lymphatic tissue organs (lymph nodes and spleen but ...
Thrombopoietin is produced in the liver by both parenchymal cells and sinusoidal endothelial cells, as well as in the kidney by proximal convoluted tubule cells. Small amounts are also made by striated muscle and bone marrow stromal cells. [5]