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A lower dose should be used in people with liver disease. [2] While it does not appear to be harmful during pregnancy, it has not been studied for this use. [3] It is unclear if it is safe for use during breastfeeding. [2] It is in the antihelmintic family of medications. [4] It works by paralyzing worms. [4] Pyrantel was initially described in ...
The available data on mebendazole, albendazole, and pyrantel pamoate use in pregnancy is limited and they are all assigned to pregnancy category level C. Treatment of a pinworm infection during pregnancy is only recommended for patients with significant symptoms that may be causing adverse effects to the pregnant woman such as loss of sleep and ...
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Pyrantel pamoate – effective against most parasitic nematodes of the GIT; Macrocyclic lactones are glutamate-gated chloride channel agonists, [8] and include: Avermectins (including ivermectin and moxidectin) - effective against most common intestinal worms, except tapeworms, for which praziquantel is commonly used in conjunction for mass ...
Pharmaceutical drugs formulated this way include cycloguanil pamoate, hydroxyzine pamoate, imipramine pamoate, olanzapine pamoate hydrate, oxantel pamoate, pyrantel pamoate, and pyrvinium pamoate. Pamoic acid has agonist activity for the orphan G protein-coupled receptor GPR35 by which it activates ERK and beta-arrestin2 , and causes ...
Similarly to pyrantel, oxantel depolarises the neurons of gastrointestinal parasites 100x more than acetylcholine, causing sustained muscular contraction, causing the parasites to die by spastic paralysis. This anthelmintic is commonly used to treat domestic animals as well as livestock, and resistance has been reported in both groups of animals.
In the package insert of a German pyrantel drug ("Helmex"), it says dosage is 10mg/kg, with one tablet containing 720mg of pyrantel embonate equivalent to 250mg of pure pyrantel. I will mark the passage with citation needed. --Victor--H 09:28, 19 July 2011 (UTC) Per Reese's insert, dosage is 11mg/ml for pyrantel base.
Drenching Merino hoggets, Walcha, NSW U.S. soldiers treating animals with de-worming medication in Eswatini during VETCAP. Deworming (sometimes known as worming, drenching or dehelmintization) is the giving of an anthelmintic drug (a wormer, dewormer, or drench) to a human or animals to rid them of helminths parasites, such as roundworm, flukes and tapeworm.