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Amino acid substitutions in OXA enzymes can also give the ESBL phenotype. While most ESBLs have been found in E. coli, K. pneumoniae, and other Enterobacteriaceae, the OXA-type ESBLs have been found mainly in P. aeruginosa. OXA-type ESBLs have been found mainly in Pseudomonas aeruginosa isolates from Turkey and France. The OXA beta-lactamase ...
The genus Klebsiella was named after the German microbiologist Edwin Klebs (1834–1913). [citation needed] It is also known as Friedlander's bacillum in honor of Carl Friedländer, a German pathologist, who proposed that this bacterium was the etiological factor for the pneumonia seen especially in immunocompromised individuals such as people with chronic diseases or alcoholics.
In 2010, a gene bla CTX-M-15 responsible for coding CTX-M-15 extended-spectrum β-lactamase (ESBL) jumped from its chromosome to its plasmid, which was then shared among several bacteria. ESBL confers resistance to pathogenic bacterial strains. This caused the development of antibiotic resistance in almost all known pathogenic bacteria at that ...
A 29% mortality rate was seen in patients with CRKp infection compared to a 25% mortality rate in patients with CSKp infections that produced extended-spectrum beta-lactamase (ESBL). Both mortality rates were considerably higher than that of patients with drug-susceptible urosepsis . [ 13 ]
Multidrug resistant Gram-negative bacteria (MDRGN bacteria) are a type of Gram-negative bacteria with resistance to multiple antibiotics.They can cause bacteria infections that pose a serious and rapidly emerging threat for hospitalized patients and especially patients in intensive care units. [1]
She is a co-author of a study published in 2024 that found unreliable pulse oximeter readings might limit the way Black patients with heart failure qualify for those potentially lifesaving procedures.
In further clinical trials from Novo Nordisk, 83 people taking semaglutide experienced gallbladder-related events (mainly gallstones), compared to just 39 patients on a placebo.
E. americana is an organism with simple nutritional needs that can survive in water and citrate solution, and preferentially grows at 4°C. Domestic sources of water, including air conditioning units, ice baths, and wound irrigation systems, have been cited as sources of infection.