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Multiple system atrophy (MSA) is a rare neurodegenerative disorder [1] characterized by tremors, slow movement, muscle rigidity, postural instability (collectively known as parkinsonism), autonomic dysfunction and ataxia.
Additional Parkinson-plus syndromes include Pick's disease and olivopontocerebellar atrophy. [7] The latter is characterized by ataxia and dysarthria, and may occur either as an inherited disorder or as a variant of multiple system atrophy. MSA is also characterized by autonomic failure, formerly known as Shy–Drager syndrome. [8]
People with multiple system atrophy usually have a progressive loss of function and are eventually bedridden. Lewy body dementia is a progressive disease with a survival rate of five to eight ...
There are three main types of synucleinopathy: Parkinson's disease (PD), dementia with Lewy bodies (DLB), and multiple system atrophy (MSA). [1] Other rare disorders, such as various neuroaxonal dystrophies, also have α-synuclein pathologies. [2]
Gregor Karl Wenning (21 March 1964 – 11 February 2024) was a German neurologist best known for his clinical and scientific work in Parkinson's disease and atypical Parkinsonian disorders, particularly multiple system atrophy (MSA).
The prevalence of Multiple System Atrophy (MSA) is increasing worldwide which is a major market driver. As per recent studies, the prevalence of MSA is estimated to be around 4 to 5 cases per 100,000 people. The increasing aging population globally is considered to be one of the main reasons for the rising prevalence.
Pages in category "Deaths from multiple system atrophy" The following 33 pages are in this category, out of 33 total. This list may not reflect recent changes .
Susana Schnarndorf Ribeiro (Porto Alegre, October 12, 1967) is a Brazilian Paralympic swimmer.In 2005, after a lengthy triathlon career, at the age of 37, Schnarndorf began to experience the first symptoms of a mysterious degenerative disease that was later diagnosed as multiple system atrophy (MSA).