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Although much is known about the mechanisms behind the spread of cholera, researchers still do not have a full understanding of what makes cholera outbreaks happen in some places and not others. Lack of treatment of human feces and lack of treatment of drinking water greatly facilitate its spread.
Although much is known about the mechanisms behind the spread of cholera, this has not led to a full understanding of what makes cholera outbreaks happen in some places and not others. Lack of treatment of human feces and lack of treatment of drinking water greatly facilitate its spread.
Cholera toxin (also known as choleragen and sometimes abbreviated to CTX, Ctx or CT) is an AB5 multimeric protein complex secreted by the bacterium Vibrio cholerae. [ 1 ] [ 2 ] CTX is responsible for the massive, watery diarrhea characteristic of cholera infection. [ 3 ]
Cholera is a bacterial infection of the intestines that leads to severe diarrhea and rapid dehydration, "which can quickly become life-threatening without treatment," says Dr. Jason Nagata, a ...
The Broad Street cholera outbreak (or Golden Square outbreak) was a severe outbreak of cholera that occurred in 1854 near Broad Street (now Broadwick Street) in Soho, London, England, during the worldwide 1846–1860 cholera pandemic.
The bacterium as the cause of cholera was discovered by Robert Koch in 1884. Sambhu Nath De isolated the cholera toxin and demonstrated the toxin as the cause of cholera in 1959. The bacterium has a flagellum (a tail like structure) at one pole and several pili throughout its cell surface. It undergoes respiratory and fermentative metabolism.
The 2010s Haiti cholera outbreak was the first modern large-scale outbreak of cholera—a disease once considered under control largely due to the invention of modern sanitation. The disease was reintroduced to Haiti in October 2010, not long after the disastrous earthquake earlier that year, and since then cholera has spread across the country ...
Cholera ravaged northern Africa in 1865 and southeastward to Zanzibar, killing 70,000 in 1869–70. [35] Cholera claimed 90,000 lives in Russia in 1866. [36] The epidemic of cholera that spread with the Austro-Prussian War (1866) is estimated to have killed 165,000 people in the Austrian Empire. [37] In 1867, 113,000 died from cholera in Italy.