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Parietal cells (also known as oxyntic cells) are epithelial cells in the stomach that secrete hydrochloric acid (HCl) and intrinsic factor. These cells are located in the gastric glands found in the lining of the fundus and body regions of the stomach. [1] They contain an extensive secretory network of canaliculi from which the HCl is secreted ...
The epithelial lining of the gland ducts is of the same character and is continuous with the general epithelial lining of the stomach. The sodium-iodide symporter (SIP) is expressed in all the surface mucous cells (at the basolateral membrane) but not in the mucous neck cells.
Mucus is released in the stomach and intestine, and serves to lubricate and protect the inner mucosa of the tract. It is composed of a specific family of glycoproteins termed mucins and is generally very viscous. Mucus is made by two types of specialized cells termed mucous cells in the stomach and goblet cells in the intestines. Signals for ...
Involves in epithelial cell maturation as well as goblet and Paneth cell differentiation. Required for the small intestinal identity during development. In IEC-6 cells, conditional expression induced enterocyte and goblet like cells: 21081128 [13] 19386267 [14] 8552090 [15] CTNNB1: Catenin, beta: Paneth cell differentiation. Essential for stem ...
The brush border on the apical surface of the epithelial cells is covered with glycocalyx, which is composed of oligosaccharides attached to membrane glycoproteins and glycolipids. [7] TEM image of a thin section cut through an epithelial cell showing the luminal surface (apical end) of the cell packed with microvilli that make up the absorbing ...
By layer, epithelium is classed as either simple epithelium, only one cell thick (unilayered), or stratified epithelium having two or more cells in thickness, or multi-layered – as stratified squamous epithelium, stratified cuboidal epithelium, and stratified columnar epithelium, [8]: 94, 97 and both types of layering can be made up of any of ...
Moreover, they can migrate through the epithelium with the help of interactions with epithelial cells. [23] Most of these cells express Vγ7 in mice and Vγ4 in humans. Their function resides in the protection of the intestinal barrier against pathogens early in the infection and later they quench the inflammation and protect the barrier from ...
Epithelioid cells gather around the focus of necrosis, in direct contact with the necrotic masses, forming a kind of boundary zone.. Structurally, epithelioid cells (when examined by light microscopy after stained with hematoxylin and eosin), are elongated, with finely granular, pale eosinophilic (pink) cytoplasm, and central, ovoid nuclei (oval or elongate), which are less dense than that of ...