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Preliminary screening for locomotor effects is needed to determine a false positive results. [ 2 ] Due to the flaws in animal modeling the LDB is best done in a battery of anxiety modeling tests with high predictive validity to determine the potential therapeutic value of a novel agent .
Over two million prescriptions for paroxetine were written for children or adolescents in the US in 2002. [29]Funded by SmithKline Beecham, the acute phase of study 329 was an eight-week, double-blind, randomized clinical trial conducted in 12 university or hospital psychiatric departments in the United States and Canada between 1994 and 1997.
TDEV is a metric often used to determine an aspect of the quality of timing signals in telecommunication applications and is a statistical analysis of the phase stability of a signal over a given period.
An institutional review board (IRB), also known as an independent ethics committee (IEC), ethical review board (ERB), or research ethics board (REB), is a committee at an institution that applies research ethics by reviewing the methods proposed for research involving human subjects, to ensure that the projects are ethical. The main goal of IRB ...
Technetium (99m Tc) sestamibi (commonly sestamibi; USP: technetium Tc 99m sestamibi; trade name Cardiolite) is a pharmaceutical agent used in nuclear medicine imaging.The drug is a coordination complex consisting of the radioisotope technetium-99m bound to six (sesta=6) methoxyisobutylisonitrile (MIBI) ligands.
Most radiation therapy is planned using the results of a 3D CT scan. A 3D scan largely presents a snapshot of the body at a particular point in time, however due to the time of the acquisition, in which the patient is likely to have moved in some way (even if only breathing), there will be an element of blurring or averaging in the 3D scan. [ 6 ]
Shulgin Ratings typically include three components. An identification of the chemical being ingested, a dosage, and a descriptive narrative including the ratings themselves used to describe various moments in time. The chemical itself must be clearly identified, preferably using chemical nomenclature, as opposed to popular or "street" names.
SeHCAT is a taurine-conjugated bile acid analog which was synthesized for use as a radiopharmaceutical to investigate in vivo the enterohepatic circulation of bile salts. [2] By incorporating the gamma-emitter 75 Se into the SeHCAT molecule, the retention in the body or the loss of this compound into the feces could be studied easily using a standard gamma camera, available in most clinical ...