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Doxepin is a mixture of and stereoisomers with an approximate ratio of 85:15. [5] When doxepin was developed, no effort was made to separate or balance the mixture following its synthesis, resulting in the asymmetric ratio. [5] (Z)-Doxepin is more active as an inhibitor of serotonin and norepinephrine reuptake than (E)-doxepin. [5]
L'Histoire de Babar, le petit éléphant (The story of Babar, the little elephant), FP 129, is a composition for narrator and piano by Francis Poulenc, based on Histoire de Babar and written from 1940. Orchestral versions were later written by Jean Françaix and David Matthews.
The character has also appeared in a number of films. The first two of Jean de Brunhoff's Babar books have inspired two major concert works: L'Histoire de Babar, le petit éléphant (The Story of Babar, the Little Elephant) by Francis Poulenc in 1940; and The Travels of Babar (Le Voyage de Babar) by Raphael Mostel in 1994.
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Depakote (valproic acid/sodium valproate) – an antiepileptic and mood stabilizer used to treat bipolar disorder, neuropathic pain and others; sometimes called an antimanic medication.
Created by Jean de Brunhoff between 1931 and 1937, Babar's Kingdom, also known as the Elephant Country (French: le pays des Éléphants), is a fictional country supposedly in West Africa with French characteristics that is composed of elephants and other animals, which are usually bipedal and "civilized".
The antidepressant drug doxepin has been associated with a number of different adverse effects, including the following. [1] [2] [3] The incidence of these adverse effects is not totally known as the scarcity of well-designed clinical trials involving doxepin prohibits it.
Cidoxepin (former developmental code name P-4599), also known as cis-doxepin or (Z)-doxepin, is a tricyclic antidepressant which was developed in the 1960s but was never marketed. [ 1 ] [ 2 ] It is the cis or ( Z ) stereoisomer of doxepin , a mixture of ( E ) and ( Z ) isomers that is used commercially in a ratio of approximately 85:15 with ...