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  2. Waldenström macroglobulinemia - Wikipedia

    en.wikipedia.org/wiki/Waldenström_macroglobulinemia

    It is characterized by having high levels of a circulating antibody, immunoglobulin M (IgM), which is made and secreted by the cells involved in the disease. Waldenström macroglobulinemia is an "indolent lymphoma" (i.e., one that tends to grow and spread slowly) and a type of lymphoproliferative disease which shares clinical characteristics ...

  3. Bing–Neel syndrome - Wikipedia

    en.wikipedia.org/wiki/Bing–Neel_syndrome

    Bing–Neel syndrome (BNS) is an extremely rare neurologic complication of Waldenström macroglobulinemia (WM), which is a chronic lymphoproliferative disorder. [1] There's no clear definition of BNS but what is known so far is that unlike WM, It involves the central nervous system (CNS), infiltrated by differentiated malignant B cells and by having hyperglobulinemia. [2]

  4. Jan G. Waldenström - Wikipedia

    en.wikipedia.org/wiki/Jan_G._Waldenström

    Waldenström first described, in 1944, patients with a disease that has subsequently been named for him, Waldenström's macroglobulinemia, a "hyperviscosity syndrome" in which symptoms are caused by abnormal lymphocytes that prevent normal bone marrow function, which causes anemia and hepatosplenomegaly, and secrete large immunoglobulins ...

  5. Cellectar's blood cancer therapy succeeds in late-stage study

    www.aol.com/news/cellectars-blood-cancer-therapy...

    In the study, 75.6% of patients with Waldenstrom's macroglobulinemia (WM) saw cancer decrease in size or disappear after treatment with Cellectar's therapy iopofosine.

  6. Macroglobulinemia - Wikipedia

    en.wikipedia.org/wiki/Macroglobulinemia

    Macroglobulinemia is the presence of increased levels of macroglobulins in the circulating blood.It is a plasma cell dyscrasia, resembling leukemia, with cells of lymphocytic, plasmacytic, or intermediate morphology, which secrete a monoclonal immunoglobulin M component.

  7. Bence Jones protein - Wikipedia

    en.wikipedia.org/wiki/Bence_Jones_protein

    A crystal of Bence Jones protein. Bence Jones protein is a monoclonal globulin protein or immunoglobulin light chain found in the urine, with a molecular weight of 22–24 kDa. [1]

  8. Rouleaux - Wikipedia

    en.wikipedia.org/wiki/Rouleaux

    This is a nonspecific indicator of the presence of disease. [1] Rouleaux formation on patient vaginal swab wet smear. Conditions that cause rouleaux formation include infections, multiple myeloma, Waldenström's macroglobulinemia, inflammatory and connective tissue disorders, and cancers.

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