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A cerebroprotectant (formerly known as a neuroprotectant) is a drug that is intended to protect the brain after the onset of acute ischemic stroke. [1] As stroke is the second largest cause of death worldwide and a leading cause of adult disability, over 150 drugs have been tested in clinical trials to provide cerebroprotection.
When someone has a stroke, a blood vessel to the brain bursts or is blocked by a clot. The result: Part of the brain cannot get the oxygen and nutrients it needs from blood, so brain cells die ...
The use of intravenous rtPA therapy can be advocated in patients who arrive to stroke unit and can be fully evaluated within 3 hours of the onset. The quicker rTPA is started, the better the outcome for the patient. [29] If cerebral infarction is caused by a thrombus occluding blood flow to an artery supplying the brain, definitive therapy is ...
Alteplase, sold under the brand name Activase among others, is a biosynthetic form of human tissue-type plasminogen activator (t-PA). It is a thrombolytic medication used to treat acute ischemic stroke, acute ST-elevation myocardial infarction (a type of heart attack), pulmonary embolism associated with low blood pressure, and blocked central venous catheter. [5]
Stroke is a medical condition in which poor blood flow to a part of the brain causes cell death. [5] There are two main types of stroke: ischemic, due to lack of blood flow, and hemorrhagic, due to bleeding. [5]
Anticoagulants are drugs used to prevent the formation of blood clots, reducing the risk of stroke, heart attack and pulmonary embolism. Heparin and warfarin are used to inhibit the formation and growth of existing thrombi, with the former used for acute anticoagulation while the latter is used for long-term anticoagulation. [8]
Oral medications used for the treatment of spasticity include: diazepam (Valium), dantrolene sodium, baclofen, tizanidine, clonidine, gabapentin, [59] [61] [62] and even cannabinoid-like compounds.³ The exact mechanism of these medications is not fully understood, but they are thought to act on neurotransmitters or neuromodulators within the ...
The therapy involves breathing pure oxygen in a chamber with above-normal air pressure. Some treatments are endorsed by medical experts, but not all. Hyperbaric oxygen therapy is touted as ...