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A parotidectomy is the surgical excision (removal) of the parotid gland, the major and largest of the salivary glands. The procedure is most typically performed due to neoplasms [1] (tumors), which are growths of rapidly and abnormally dividing cells. Neoplasms can be benign (non-cancerous) or malignant (cancerous).
However, the condition may arise anywhere minor salivary glands are located. [nb 1] It has also been occasionally reported to involve the major salivary glands. [2] [3] It may be present only on one side, or both sides. [1] The lesion typically is 1–4 cm in diameter. [4] Initially, the lesion is a tender, erythematous (red) swelling. Later ...
Salivary gland dysfunction refers to either xerostomia (the symptom of dry mouth) or salivary gland hypofunction (reduced production of saliva); it is associated with significant impairment of quality of life. [34] Following radiotherapy of the head and neck region, salivary gland dysfunction is a predictable side-effect. [34]
Acinic cell carcinoma is a malignant tumor representing 2% of all salivary tumors. 90% of the time found in the parotid gland, 10% intraorally on buccal mucosa or palate. The disease presents as a slow growing mass, associated with pain or tenderness in 50% of the cases.
Treatment options may include surgery, radiation, and chemotherapy. Icotinib has been temporarily effective at treating salivary gland-like carcinoma of the lung but loses efficiency after three months. [7]
Radiation therapy for cancers of the head and neck (including brachytherapy for thyroid cancers) where the salivary glands are close to or within the field irradiated is another major cause of xerostomia. [8] A radiation dose of 52 Gy is sufficient to cause severe salivary dysfunction.
Sialoendoscopy is a minimally invasive technique that allows for salivary gland surgery for the safe and effective treatment of obstructive salivary gland disorders and other conditions of the salivary glands. During sialoendoscopy a small endoscope is placed into the salivary glands through the salivary ducts that empty into the mouth.
Radiation mask used in the treatment of throat cancer. Radiation therapy is the most common form of treatment. There are different forms of radiation therapy, including 3D conformal radiation therapy, intensity-modulated radiation therapy, particle beam therapy, and brachytherapy, which are commonly used in the treatment of cancers of the head ...