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551 11998 Ensembl ENSG00000101200 ENSMUSG00000037727 UniProt P01185 P35455 RefSeq (mRNA) NM_000490 NM_009732 RefSeq (protein) NP_000481 NP_033862 Location (UCSC) Chr 20: 3.08 – 3.08 Mb Chr 2: 130.42 – 130.42 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Human vasopressin, also called antidiuretic hormone (ADH), arginine vasopressin (AVP) or argipressin, is a hormone synthesized ...
The arginine vasopressin (AVP) gene is a gene whose product is proteolytically cleaved to produce vasopressin (also known as antidiuretic hormone or ADH), neurophysin II, and a glycoprotein called copeptin. AVP and other AVP-like peptides are found in mammals, as well as mollusks, arthropods, nematodes, and other invertebrate species. [5]
However, some of these other substances are known to be important. Dynorphin produced by vasopressin neurons is involved in regulating the phasic discharge patterning of vasopressin neurons, and nitric oxide produced by both neuronal types is a negative-feedback regulator of cell activity. Oxytocin neurons also make dynorphin; in these neurons ...
Oxytocin and vasopressin (also called anti-diuretic hormone), the two neurohypophysial hormones of the posterior pituitary gland (the neurohypophysis), are secreted from the nerve endings of magnocellular neurosecretory cells into the systemic circulation.
This can be due to injury to the hypothalamus or pituitary gland or due to genetics. [1] Nephrogenic DI (NDI), also known as arginine vasopressin resistance (AVP-R), [5] occurs when the kidneys do not respond properly to vasopressin. [1] Dipsogenic DI is a result of excessive fluid intake due to damage to the hypothalamic thirst mechanism. [1]
It is also known as neurohypophyseal diabetes insipidus, [2] [3] referring to the posterior pituitary (neurohypophysis), which receives vasopressin from the hypothalamus in the brain, via the hypothalamo-hypophyseal tract in the pituitary stalk. This condition has only polyuria in common with diabetes. Although not mutually exclusive, with most ...
Also called the neural lobe or posterior lobe, this region constitutes the majority of the posterior pituitary and is the storage site of oxytocin and vasopressin. Sometimes (incorrectly) considered synonymous with the posterior pituitary, the pars nervosa includes Herring bodies and pituicytes .
The neurohypophysial hormones form a family of structurally and functionally related peptide hormones.Their representatives in humans are oxytocin and vasopressin.They are named after the location of their release into the blood, the neurohypophysis (another name for the posterior pituitary).