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There are also a number of other conditions that affect hands, feet, and parts of the face with associated skin color changes that need to be differentiated from acrocyanosis: Raynaud phenomenon, pernio, acrorygosis, erythromelalgia, and blue finger syndrome. The diagnosis may be challenging in some cases, especially when these syndromes co-exist.
Senile pruritus is one of the most common conditions in the elderly or people over 65 years of age with an emerging itch that may be accompanied with changes in temperature and textural characteristics. [1] [2] [3] In the elderly, xerosis, is the most common cause for an itch due to the degradation of the skin barrier over time. [4]
These injuries often affect the fingers, toes, nose, and ears since they are less commonly covered by clothing when in cold environments. [1] Affected skin becomes numb, turns white or blue, and develops blisters. [1] Frostnip is a superficial skin injury that won't freeze the skin or cause long-term damage. [8]
Doctors at the hospital decided to form a medical board for the treatment of the patient. [ 21 ] [ 22 ] Over the following year, Bajandar underwent at least 25 surgeries for the removal of the warts—weighing in excess of 5 kg (11 lb)—from his hands, feet, and legs.
Many skin conditions affect the human integumentary system—the organ system covering the entire surface of the body and composed of skin, hair, nails, and related muscle and glands. [1] The major function of this system is as a barrier against the external environment. [2]
It typically affects the hands and feet, and is typically inherited in an autosomal dominant manner, affecting the keratin genes KRT5 and KRT14. Therefore, there is a failure in keratinization, which affects the integrity and the ability of the skin to resist mechanical stresses. [citation needed]
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