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The poor response from some bipolar patients to treatment has given evidence to the concept of treatment-resistant bipolar disorder. [163] [164] Guidelines to the definition of treatment-resistant bipolar disorder and evidence-based options for its management were reviewed in 2020. [165]
Bipolar disorder – mental disorder with cyclical periods of depression and periods of elevated mood. [1] The elevated mood is significant and is known as mania , a severe elevation that can be accompanied by psychosis in some cases, or hypomania , a milder form of mania.
Bipolar disorder is a long-term mood disorder characterized by major fluctuations in mood — both high and low — that can impact daily functioning and behavior. Bipolar Disorder: 4 Types & What ...
Bipolar I disorder requires confirmation of only 1 full manic episode for diagnosis, but may be associated with hypomanic and depressive episodes as well. [7] Diagnosis for bipolar II disorder does not include a full manic episode; instead, it requires the occurrence of both a hypomanic episode and a major depressive episode. [7]
Bipolar disorder is often a lifelong condition, and patients should be followed up regularly for relapse prevention. [27] Although BP-II is thought to be less severe than BP-I in regard to symptom intensity, BP-II is associated with higher frequencies of rapid cycling and depressive episodes. [ 28 ]
Co-occurring substance misuse disorders, which are extremely common in bipolar patients, can cause a significant worsening of bipolar symptomatology and can cause the emergence of affective symptoms. The treatment options and recommendations for substance use disorders is wide but may include certain pharmacological and nonpharmacological ...