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It is a more potent derivative of triamcinolone, and is about eight times as potent as prednisone. [14] Most forms of triamcinolone acetonide are prescription drugs. In 2014, the U.S. Food and Drug Administration (FDA) made triamcinolone acetonide an over-the-counter drug in the United States in nasal spray form under the brand name Nasacort. [14]
The derivative triamcinolone acetonide is the active ingredient in various topical skin preparations (cream, lotion, ointment, aerosol spray) designed to treat such skin conditions as rash, inflammation, redness, or intense itching due to eczema [15] and dermatitis. [16]
Econazole/triamcinolone is a combination drug, consisting of econazole (an imidazole antifungal) and triamcinolone (a group III topical steroid). It is used as a topical cream against fungal skin infections , including Trichophyton mentagrophytes , T. rubrum , Epidermophyton floccosum and Candida albicans .
Latanoprost has shown ability to promote scalp hair density and pigmentation, [89] and is theorized to function at the dermal papilla. [90] A study found latanoprost ineffective on eyelashes in a patient with alopecia areata. [91] It has also been found ineffective in treatment of eyebrow hair loss. [92]
The differences in extent of percutaneous absorption in different parts of the body (percent of the total dose absorbed into the body through the skin) are as follows: [9] Sole – 0.05%; Palm – 0.1%; Forearm – 1%; Scalp – 3.5%; Face – 7%; Eyelids and genitalia – 30%
No loss of body function occurs, and the effects of alopecia areata are psychological (loss of self-image due to hair loss), although these can be severe. Loss of hair also means the scalp burns more easily in the sun. Patients may also have aberrant nail formation because keratin forms both hair and nails. [citation needed]