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Optic nerve melanocytoma does not usually produce symptoms or grow. If they slowly grow, optic nerve melanocytoma can produce afferent pupillary defects (30%), subretinal fluid (10%), and an enlarged blind spot (75%). On fundoscopic exam, the optic disc may be swollen, atrophic, or even normal. [1] Central retinal vein occlusion may occur.
Optic neuritis involving external fibers of the optic nerve causes tunnel vision. [4] Optic neuritis involving internal fibers of the optic nerve causes central scotoma. [4] lf unilateral central scotoma is detected, careful observation of the temporal visual field of other eye is essential to rule out the possibility of compressive lesions at ...
Optic gliomas are usually pilocytic tumors, and can involve the optic nerve or optic chiasm. [3] Optic gliomas are usually associated with neurofibromatosis type 1 in 30% of people with the condition. [3] Optic nerve gliomas have low mortality but extremely high prevalence of vision loss and eye-bulging exophthalmos) in children. [4]
Cancer Associated Retinopathy (CAR) also known as Carcinoma Associated Retinopathy is an immune-mediated disease affecting the retina of the eye. It is a paraneoplastic type autoimmune retinopathy associated with cancer that can cause blindness. It can be seen in association with various types of cancers.
The optic nerve can be damaged when exposed to direct or indirect injury. Direct optic nerve injuries are caused by trauma to the head or orbit that crosses normal tissue planes and disrupts the anatomy and function of the optic nerve; e.g., a bullet or forceps that physically injures the optic nerve.
Hyperviscosity syndrome [24] Polycythemia [25] Hypercoagulability [26] Protein C deficiency [27] Antiphospholipid antibodies [28] Anticardiolipin antibodies [29] Lupus anticoagulant [30] [31] Thrombocytosis [29] Subclavian steal syndrome; Malignant hypertension can cause ischemia of the optic nerve head leading to transient monocular visual ...
Pituitary apoplexy is regarded by some as distinct from Sheehan's syndrome, where the pituitary undergoes infarction as a result of prolonged very low blood pressure, particularly when caused by bleeding after childbirth. This condition usually occurs in the absence of a tumor. [4] Others regard Sheehan's syndrome as a form of pituitary apoplexy.
Ocular disc dysplasia is the most notable ocular defect of the disease. An abnormal development in the optic stalk causes optic disc dysplasia, which is caused by a mutation in the Pax2 gene. [4] The nerve head typically resembles the morning glory disc anomaly, but has also been described as a coloboma. [4]