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When a foot is exposed to constant stress, calcium deposits build up on the bottom of the heel bone. Generally, this has no effect on a person's daily life. However, repeated damage can cause these deposits to pile up on each other, causing a spur-shaped deformity, called a calcaneal (or heel) spur. [3]
First, in the "precalcific stage", something causes tendon cells to transform into other cells that can act as sites for calcium deposition. [2] This is followed by the two-part "calcific stage"; first calcium is deposited (the formative phase), then the body begins to break down the calcium deposit (the resorptive phase). [2]
One of the principal causes of arterial stiffening with age is vascular calcification. Vascular calcification is the deposition of mineral in the form of calcium phosphate salts in the smooth muscle-rich medial layer of large arteries including the aorta. DNA damage, especially oxidative DNA damage, causes accelerated vascular calcification. [11]
Calcium supplements may be a bonus for bone health. But if you’re taking these medications, your supplement might backfire. Calcium supplements may be a bonus for bone health. But if you’re ...
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Carbonated calcium-deficient hydroxyapatite is the main mineral of which dental enamel and dentin are composed. Hydroxyapatite crystals are also found in pathological calcifications such as those found in breast tumors , [ 8 ] as well as calcifications within the pineal gland (and other structures of the brain) known as corpora arenacea or ...
The plasma total calcium concentration is in the range of 2.2–2.6 mmol/L (9–10.5 mg/dL), and the normal ionized calcium is 1.3–1.5 mmol/L (4.5–5.6 mg/dL). [4] The amount of total calcium in the blood varies with the level of plasma albumin, the most abundant protein in plasma, and therefore the main carrier of protein-bound calcium in the blood.
The existence of Mönckeberg's arteriosclerosis has been disputed and it has been proposed that it is a part of a continuum of atherosclerotic disease: [19] the majority of atherosclerotic plaques contain some calcium deposits [23] [24] and calcification of the internal elastic lamina is common in pathological specimens labelled as Mönckeberg ...