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Rabies causes about 59,000 deaths worldwide per year, [6] about 40% of which are in children under the age of 15. [16] More than 95% of human deaths from rabies occur in Africa and Asia. [1] Rabies is present in more than 150 countries and on all continents but Antarctica. [1] More than 3 billion people live in regions of the world where rabies ...
Animals with "dumb" rabies appear depressed, lethargic, and uncoordinated. Gradually they become completely paralyzed. When their throat and jaw muscles are paralyzed, the animals will drool and have difficulty swallowing. In animals, rabies is a viral zoonotic neuro-invasive disease which causes inflammation in the brain and is usually fatal ...
3D still showing rabies virus structure. Rhabdoviruses have helical symmetry, so their infectious particles are approximately cylindrical in shape. They are characterized by an extremely broad host spectrum ranging from plants [citation needed] to insects [citation needed] and mammals; human-infecting viruses more commonly have icosahedral symmetry and take shapes approximating regular polyhedra.
The rabies vaccine is a vaccine used to prevent rabies. [11] There are several rabies vaccines available that are both safe and effective. [11] Vaccinations must be administered prior to rabies virus exposure or within the latent period after exposure to prevent the disease. [12]
Joseph Meister in 1885. Joseph Meister (21 February 1876 – 24 June 1940) was the first person to be inoculated against rabies by Louis Pasteur, and likely the first person to be successfully treated for the infection, which has a >99% fatality rate once symptoms set in.
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Isolated cases of rabies involving illegally smuggled pets from Africa, as well as infected animals crossing the German and French borders, do occur. [98] However, in 2024, a case of rabies was detected in a cat in the Netherlands, with laboratory tests finding the cat had been infected with the European bat lyssavirus 1 (EBLV-1). [99]
Tierkel's basic work with Martha Edson and Bob Kissling evaluating the new chicken embryo rabies vaccine, which set the basis for rabies control in the U.S. Later the same evaluation was made of polio vaccine based on the same methods. In 1946 there were 10,000 cases of canine rabies every year reported in the United States.