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  2. Hematopoietic stem cell - Wikipedia

    en.wikipedia.org/wiki/Hematopoietic_stem_cell

    Hematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent hematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. [16] [17] [13] It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an identical twin).

  3. Hematopoietic stem cell transplantation - Wikipedia

    en.wikipedia.org/wiki/Hematopoietic_stem_cell...

    Stem-cell transplantation was pioneered using bone marrow-derived stem cells by a team at the Fred Hutchinson Cancer Research Center from the 1950s through the 1970s led by E. Donnall Thomas, whose work was later recognized with a Nobel Prize in Physiology or Medicine. Thomas' work showed that bone-marrow cells infused intravenously could ...

  4. List of conditions treated with hematopoietic stem cell ...

    en.wikipedia.org/wiki/List_of_conditions_treated...

    Mucolipidosis II (I-cell disease) Fucosidosis; Aspartylglucosaminuria; Alpha-mannosidosis; Other Wolman disease (acid lipase deficiency) Immunodeficiencies. T-cell deficiencies Ataxia-telangiectasia; DiGeorge syndrome; Combined T- and B-cell deficiencies Severe combined immunodeficiency (SCID), all types; Well-defined syndromes Wiskott ...

  5. Haematopoietic system - Wikipedia

    en.wikipedia.org/wiki/Haematopoietic_system

    Haematopoietic stem cell transplantation (HSCT) is the transplantation of multipotent haematopoietic stem cells, usually derived from bone marrow, peripheral blood, or umbilical cord blood. [ 10 ] [ 11 ] [ 12 ] It may be autologous (the patient's own stem cells are used), allogeneic (the stem cells come from a donor) or syngeneic (from an ...

  6. Stem-cell therapy - Wikipedia

    en.wikipedia.org/wiki/Stem-cell_therapy

    Stem-cell therapy uses stem cells to treat or prevent a disease or condition. [1] As of 2024, the only FDA-approved therapy using stem cells is hematopoietic stem cell transplantation. [2] [3] This usually takes the form of a bone marrow or peripheral blood stem cell transplantation, but the cells can also be derived from umbilical cord blood.

  7. Stem cell - Wikipedia

    en.wikipedia.org/wiki/Stem_cell

    For over 50 years, hematopoietic stem cell transplantation (HSCT) has been used to treat people with conditions such as leukaemia and lymphoma; this is the only widely practiced form of stem-cell therapy. [94] [95] [97] As of 2016, the only established therapy using stem cells is hematopoietic stem cell transplantation. [98]

  8. History and naming of human leukocyte antigens - Wikipedia

    en.wikipedia.org/wiki/History_and_naming_of...

    HL-A1 antiserum reacts to HLA-A1 gene product, a cell surface antigen, the similar cell surface antigens are found on almost all cells in the body. The frequency of HLA-A1 alleles is: HLA-A1*0101- 17.3%, *0103- 0.016%. The frequency of *0101 is 1000 times more abundant than *0103, or 99.9% of the time you have identified the correct allele with ...

  9. Enzyme replacement therapy - Wikipedia

    en.wikipedia.org/wiki/Enzyme_replacement_therapy

    Hematopoietic stem cell (HSC) transplantation is another treatment for lysosomal storage diseases. [12] HSCs are derived from bone-marrow. [13] These cells have the ability to mature into the many cell types that comprise blood, including red blood cells, platelets, and white blood cells. [13]