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Tocolytics are used in preterm labor, which refers to when a baby is born too early before 37 weeks of pregnancy. As preterm birth represents one of the leading causes of neonatal morbidity and mortality, the goal is to prevent neonatal morbidity and mortality through delaying delivery and increasing gestational age by gaining more time for other management strategies like corticosteroids ...
Low dose aspirin is recommended to prevent pre-eclampsia and eclampsia in those at high risk. [12] Other preventative recommendations include calcium supplementation in areas with low calcium intake and treatment of prior hypertension with anti-hypertensive medications. [2] [3] Exercise during pregnancy may also be useful. [1]
Preeclampsia does not in general increase a woman's risk for developing chronic hypertension or other heart-related problems. Women with normal blood pressure who develop preeclampsia after the 20th week of their first pregnancy, short-term complications, including increased blood pressure, usually go away within about six weeks after delivery. [7]
The definitive treatment for pre-eclampsia is the delivery of the baby and placenta, but danger to the mother persists after delivery, and full recovery can take days or weeks. [13] The timing of delivery should balance the desire for optimal outcomes for the baby while reducing risks for the mother. [ 15 ]
For women with low calcium diets, there is low quality evidence to suggest that calcium supplementation during pregnancy may reduce the risk of preeclampsia. [25] Low-quality evidence also suggests that calcium supplementation may reduce the risk of the mother having the baby before 37th week of pregnancy (preterm birth). [25] [26]
Trials using low-dose aspirin, fish oil, vitamin C and E, and calcium to reduce preeclampsia demonstrated some reduction in preterm birth only when low-dose aspirin was used. [95] Even if agents such as calcium or antioxidants were able to reduce preeclampsia, a resulting decrease in preterm birth was not observed.
The onset of the disease within the first trimester leads to preterm delivery of a premature baby. [14] Preeclampsia is diagnosed in 3-5% of pregnancies that place them at risk of developing placental disease. [6] Ischemic placental disease is linked with approximately more than half of premature births. [4]
10% calcium gluconate solution (given intravenously) is the form of calcium most widely used in the treatment of low blood calcium.This form of calcium is not as well absorbed as calcium lactate, [12] and it only contains 0.93% (93 mg/dL) calcium ion (defined by 1 g weight solute in 100 mL of solution to make 1% solution w/v).