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Rheumatoid nodulosis is a cutaneous condition associated with rheumatoid arthritis, characterized by the appearance of multiple nodules, most often on the hands. [ 1 ] Signs and symptoms
Rheumatoid nodulosis is characterized by multiple subcutaneous nodules presenting with rheumatoid factors but an absence of joint complaints. The nodules are typically small and concentrated on the extensor sites of the hands and feet, sometimes accompanied by bone erosions.
Winchester syndrome was once considered to be related to a similar condition, multicentric osteolysis, nodulosis, and arthropathy (MONA). [4] [5] However, it was discovered that the two are caused by mutations found in different genes; however they mostly produce the same phenotype or clinical picture. [4] Appearances resemble rheumatoid arthritis.
Prurigo nodularis (PN), also known as nodular prurigo, is a skin disorder characterized by pruritic (), nodular lesions, which commonly appear on the trunk, arms and legs. [1]
The condition should be differentially diagnosed from juvenile rheumatoid arthritis and other genetic skeletal dysplasias as Multicentric Osteolysis, Nodulosis, and Arthropathy. [ 5 ] [ 6 ] Treatment
Caplan syndrome presents with cough and shortness of breath in conjunction with features of rheumatoid arthritis, such as painful joints and morning stiffness. Examination should reveal tender, swollen metacarpophalangeal joints and rheumatoid nodules; auscultation of the chest may reveal diffuse crackles that do not disappear on coughing or taking a deep breath.
4313 17390 Ensembl ENSG00000087245 ENSMUSG00000031740 UniProt P08253 P33434 RefSeq (mRNA) NM_004530 NM_001127891 NM_001302508 NM_001302509 NM_001302510 NM_008610 RefSeq (protein) NP_001121363 NP_001289437 NP_001289438 NP_001289439 NP_004521 NP_032636 Location (UCSC) Chr 16: 55.39 – 55.51 Mb Chr 8: 93.55 – 93.58 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse 72 kDa type IV ...
Rheumatoid nodulosis (accelerated rheumatoid nodulosis) Rheumatoid vasculitis; Rowell's syndrome; Scleredema adultorum (Bushke disease, scleredema diabeticorum, scleredema adultorum of Buschke, scleredema of Buschke) Silicosis; Sjögren's syndrome (Mikulicz disease, Sicca syndrome) Subacute cutaneous lupus erythematosus; Systemic lupus ...