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The nervous and endocrine systems often act together in a process called neuroendocrine integration, to regulate the physiological processes of the human body. Neuroendocrinology arose from the recognition that the brain, especially the hypothalamus , controls secretion of pituitary gland hormones, and has subsequently expanded to investigate ...
A delicate balance of the enzymes secretases regulate the amyloid-beta accumulation. Recently, a link between cholinergic neuronal activity and the activity of alpha-secretase has been highlighted, [ 19 ] which can discourage amyloid-beta proteins deposition in brain of patients with Alzheimer's disease.
During times of stress, the body reacts by secreting stress hormones into the bloodstream. Stress can cause acute and chronic changes in certain brain areas which can cause long-term damage. [4] Over-secretion of stress hormones most frequently impairs long-term delayed recall memory, but can enhance short-term, immediate recall memory.
Retrogenesis is a medical hypothesis that just as the fetus goes through a process of neurodevelopment beginning with neurulation and ending with myelination, the brains of people with Alzheimer's disease go through a reverse neurodegeneration process starting with demyelination and death of axons (white matter) and ending with the death of ...
Doctors used hormones taken from cadavers before a synthetic version became available. It’s possible that other patients who received cadaver-derived hormones are at higher risk of Alzheimer’s ...
The complementary process that involves increase in quantities of cellular components is called upregulation. [ 1 ] An example of downregulation is the cellular decrease in the expression of a specific receptor in response to its increased activation by a molecule, such as a hormone or neurotransmitter , which reduces the cell's sensitivity to ...
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