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There are 407 FDA-approved drugs which may interact with lomustine. Many of these interactions are due to severe side-effects of this chemotherapy, which are incompatible other drugs' known side effects. [18] Lomustine is contraindicated in the administration of most live vaccines during treatment, due to infection risk.
Some chemotherapy drugs are used in diseases other than cancer, such as in autoimmune disorders, [166] and noncancerous plasma cell dyscrasia. In some cases they are often used at lower doses, which means that the side effects are minimized, [166] while in other cases doses similar to ones used to treat cancer are used.
Corticotrophin, this drug's active ingredient, has been used since the 1950s and cost as little as $40 a month back in 2001. The version Mallinckrodt Pharmaceuticals got approved in 2010 runs ...
Side effects of etifoxine include slight drowsiness and headache. [2] [9] Rarely, etifoxine can cause benign skin eruptions or rashes and allergic reactions such as hives and angioedema. [2] [8] [1] Etifoxine shows less adverse effects of anterograde amnesia, sedation, impaired psychomotor performance, and withdrawal syndromes than those of ...
Common side effects include low blood cell counts, fever, nausea, diarrhea, loss of appetite, cough, and rash. [3] Other severe side effects include allergic reactions and increased risk of infection. [3] Use in pregnancy is known to harm the baby. [3] Bendamustine is in the alkylating agents family of medication. [3]
Ifosfamide is a DNA-damaging alkylating agent, belonging to the same class of chemotherapy drugs as cyclophosphamide. It is a prodrug, meaning that It has to be converted by CYP450 into its main active metabolites-(Iso)phosphoramide mustards. These metabolites form DNA cross links mainly at Guanine N-7 positions. [5]
Chemo-protective agents are common drugs and like many other drugs, may have side effects of their own. Each agent has different side effects though the most common consist of dizziness, sleepiness, nausea, fever, etc. [ 3 ] It is important to discuss the side effects of these drugs with a doctor before using them to combat any type of ...
The main side effects of vincristine are chemotherapy-induced peripheral neuropathy, hyponatremia, constipation, and hair loss. Vincristine-induced neuropathy is the main dose-limiting side effect. [9] Chemotherapy-induced peripheral neuropathy can be severe, and may be a reason to reduce or avoid using vincristine.