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Lysine acetylsalicylate, also known as aspirin DL-lysine or lysine aspirin, is a more soluble form of acetylsalicylic acid (aspirin). As with aspirin itself, it is a nonsteroidal anti-inflammatory drug (NSAID) with analgesic, anti-inflammatory, antithrombotic and antipyretic properties. [ 1 ]
However, more recent trials were not able to replicate similar outcomes using low dose aspirin in low body weight (<70 kg) in specific subset of population studied i.e. elderly and diabetic population, and more evidence is required to study the effect of high dose aspirin in high body weight (≥70 kg). [108] [109] [110]
An estimated 10–20% of NSAID patient's experience dyspepsia, and NSAID-associated upper gastrointestinal adverse events are estimated to result in 103,000 hospitalizations and 16,500 deaths per year in the United States, and represent 43% of drug-related emergency visits. Many of these events are avoidable; a review of physician visits and ...
Aspirin helps prevent blood clots from forming, which is the leading cause of heart attack and stroke, but the drug also carries a risk of bleeding. That risk can outweigh aspirin’s benefits in ...
Nonsteroidal anti-inflammatory drugs (NSAIDs) belongs to a drug class that has both analgesic and anti-inflammatory effects. [25] NSAIDs can often be found over-the-counter including ibuprofen and naproxen. There may be exceptions to which some NSAIDs are only available by prescription.
some NSAIDs are marketed for cramps, but any NSAID would work [60] minor trauma, such as a bruise, abrasions, sprain: paracetamol, NSAIDs [60] opioids not recommended [60] severe trauma, such as a wound, burn, bone fracture, or severe sprain opioids [60] more than two weeks of pain requiring opioid treatment is unusual [60] strain or pulled muscle