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The impairment of bone metabolism causes inadequate bone mineralization. Osteomalacia in children is known as rickets, and because of this, use of the term "osteomalacia" is often restricted to the milder, adult form of the disease. Signs and symptoms can include diffuse body pains, muscle weakness, and fragility of the bones.
An excess of vitamin D causes abnormally high blood concentrations of calcium, which can cause overcalcification of the bones, soft tissues, heart and kidneys. In addition, hypertension can result. [2] Symptoms of vitamin D toxicity may include the following: Dehydration; Vomiting; Diarrhea; Decreased appetite; Irritability; Constipation ...
Symptoms: Abdominal pain, bone pain, confusion, depression, weakness [1] [2] Complications: Kidney stones, abnormal heart rhythm, cardiac arrest [1] [2] Causes: Primary hyperparathyroidism, cancer, sarcoidosis, tuberculosis, Paget disease, multiple endocrine neoplasia, vitamin D toxicity [1] [3] Diagnostic method
Vitamin D 3 was shown to result from the ultraviolet irradiation of 7-dehydrocholesterol. Although a chemical nomenclature for vitamin D forms was recommended in 1981, [11] alternative names remain commonly used. [3] Chemically, the various forms of vitamin D are secosteroids, meaning that one of the bonds in the steroid rings is broken. [12]
Vitamin D deficiency, especially in early life, is linked to an increased risk of autoimmune conditions, such as type 1 diabetes. Autoimmune diseases can be caused by a failure of T cells, a type ...
Vitamin D also helps clear beta amyloid, a protein that plays a role in Alzheimer’s disease, Merrill points out. This is “the same mechanism targeted by new prescription drugs in Alzheimer’s ...