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The Reference Sequence (RefSeq) database [1] is an open access, annotated and curated collection of publicly available nucleotide sequences (DNA, RNA) and their protein products. RefSeq was introduced in 2000.
This enzyme has a pH optimum of 7.4 and temperature optimum of 30 °C. [6] Telokin is an acidic protein with a PI value of 4-5 and 17-kDa with an amino acid sequence that is identical to the C terminus of the 130-kDa myosin light chain kinase (MLCK), although it is expressed as a separate protein and produced by an alternate promoter of the ...
The translation table list below follows the numbering and designation by NCBI. [2] Four novel alternative genetic codes were discovered in bacterial genomes by Shulgina and Eddy using their codon assignment software Codetta, and validated by analysis of tRNA anticodons and identity elements; [ 3 ] these codes are not currently adopted at NCBI ...
The GenBank sequence database is an open access, annotated collection of all publicly available nucleotide sequences and their protein translations. It is produced and maintained by the National Center for Biotechnology Information (NCBI; a part of the National Institutes of Health in the United States) as part of the International Nucleotide Sequence Database Collaboration (INSDC).
The sequence in brackets (GCC) is the motif with unknown biological impact. [5] There are variations within Kozak consensus sequence, such as G or A is observed three nucleotides upstream (at position -3) of AUG. Bases between positions -3 and +4 of Kozak sequence have the most significant impact on translational efficiency.
The National Center for Biotechnology Information (NCBI) [1] [2] is part of the (NLM), a branch of the National Institutes of Health (NIH). It is approved and funded by the government of the United States. The NCBI is located in Bethesda, Maryland, and was founded in 1988 through legislation sponsored by US Congressman Claude Pepper.
The Entrez (IPA:) [1] Global Query Cross-Database Search System is a federated search engine, or web portal that allows users to search many discrete health sciences databases at the National Center for Biotechnology Information (NCBI) website. [2] The NCBI is a part of the National Library of Medicine (NLM), which is itself a department of the ...
The dbSNP accepts apparently neutral polymorphisms, polymorphisms corresponding to known phenotypes, and regions of no variation. It was created in September 1998 to supplement GenBank, NCBI’s collection of publicly available nucleic acid and protein sequences. [2] In 2017, NCBI stopped support for all non-human organisms in dbSNP. [3]