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  2. Meiosis - Wikipedia

    en.wikipedia.org/wiki/Meiosis

    Later on, during fertilisation, the haploid cells produced by meiosis from a male and a female will fuse to create a zygote, a cell with two copies of each chromosome again. Errors in meiosis resulting in aneuploidy (an abnormal number of chromosomes) are the leading known cause of miscarriage and the most frequent genetic cause of ...

  3. Homologous recombination - Wikipedia

    en.wikipedia.org/wiki/Homologous_recombination

    The DSBR pathway is unique in that the second 3' overhang (which was not involved in strand invasion) also forms a Holliday junction with the homologous chromosome. The double Holliday junctions are then converted into recombination products by nicking endonucleases, a type of restriction endonuclease which cuts only one DNA strand. The DSBR ...

  4. Sexual reproduction - Wikipedia

    en.wikipedia.org/wiki/Sexual_reproduction

    This is typical in animals, though the number of chromosome sets and how that number changes in sexual reproduction varies, especially among plants, fungi, and other eukaryotes. [ 2 ] [ 3 ] In placental mammals , sperm cells exit the penis through the male urethra and enter the vagina during copulation , [ 4 ] [ 5 ] while egg cells enter the ...

  5. Gene conversion - Wikipedia

    en.wikipedia.org/wiki/Gene_conversion

    The ordinary segregation pattern of an allele pair (Aa) among the 4 products of meiosis is 2A:2a. Detection of infrequent gene conversion events (e.g. 3:1 or 1:3 segregation patterns during individual meioses) provides insight into the alternate pathways of recombination leading either to crossover or non-crossover chromosomes.

  6. Leptotene stage - Wikipedia

    en.wikipedia.org/wiki/Leptotene_stage

    The leptotene stage, also known as leptonema, is the first of five substages of prophase I during meiosis, the specialized cell division that reduces the chromosome number by half to produce haploid gametes in sexually reproducing organisms.

  7. Cell division - Wikipedia

    en.wikipedia.org/wiki/Cell_division

    Meiosis undergoes two divisions resulting in four haploid daughter cells. Homologous chromosomes are separated in the first division of meiosis, such that each daughter cell has one copy of each chromosome. These chromosomes have already been replicated and have two sister chromatids which are then separated during the second division of ...

  8. Genetic linkage - Wikipedia

    en.wikipedia.org/wiki/Genetic_linkage

    Genetic linkage is the tendency of DNA sequences that are close together on a chromosome to be inherited together during the meiosis phase of sexual reproduction.Two genetic markers that are physically near to each other are unlikely to be separated onto different chromatids during chromosomal crossover, and are therefore said to be more linked than markers that are far apart.

  9. Pachytene - Wikipedia

    en.wikipedia.org/wiki/Pachytene

    The pachytene stage (/ˈpækɪtiːn/ PAK-i-teen; from Greek words meaning "thick threads". [1]: 27 ), also known as pachynema, is the third stage of prophase I during meiosis, the specialized cell division that reduces chromosome number by half to produce haploid gametes.