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There are three main treatment options available to treat soft tissue sarcoma in cats and dogs: surgery, radiation therapy, and chemotherapy. Surgery alone or in combination with radiation therapy are used to treat the tumor at its original location, and chemotherapy is usually used to prevent or at least slow down the process of metastasis in ...
It is possible for cats to have a granuloma form after vaccination, so it is important to differentiate between the two before radical surgery is performed. One guideline for biopsy is if a growth is present three months after surgery, if a growth is greater than two centimeters, or if a growth is becoming larger one month after vaccination. [1]
Dermatofibrosarcoma protuberans (DFSP) [2] is a rare locally aggressive malignant cutaneous soft-tissue sarcoma. DFSP develops in the connective tissue cells in the middle layer of the skin (dermis). [3] Estimates of the overall occurrence of DFSP in the United States are 0.8 to 4.5 cases per million persons per year.
In cats, fibrosarcoma occurs on the skin. It is also the most common vaccine-associated sarcoma. [9] In 2014, Merial launched Oncept IL-2 in Europe for the management of such feline fibrosarcomas. [10] Bostock DE, et al. performed a study of cats that had fibrosarcomas excised and were followed for a minimum of three years, or until death.
Myofibroblastic cells are plumper with more abundant cytoplasm and more prominent nucleoli; they express smooth muscle marker proteins such as smooth muscle actins, desmin, and caldesmon. [2] The World Health Organization further classified FMTs into four tumor forms based on their varying levels of aggressiveness: benign, intermediate (locally ...
Low-grade fibromyxoid sarcoma (LGFMS) is a rare type of low-grade sarcoma first described by H. L. Evans in 1987. [1] LGFMS are soft tissue tumors of the mesenchyme-derived connective tissues; on microscopic examination, they are found to be composed of spindle-shaped cells that resemble fibroblasts. [2]