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Intestinal villi (sg.: villus) are small, finger-like projections that extend into the lumen of the small intestine. Each villus is approximately 0.5–1.6 mm in length (in humans), and has many microvilli projecting from the enterocytes of its epithelium which collectively form the striated or brush border. Each of these microvilli are about 1 ...
Goblet cells secrete mucus, which lubricates the passage of food along and protects the intestinal wall from digestive enzymes. In the small intestine, villi are folds of the mucosa that increase the surface area of the intestine. The villi contain a lacteal, a vessel connected to the lymph system that aids in the removal of lipids and tissue ...
The barrier formed by the intestinal epithelium separates the external environment (the contents of the intestinal lumen) from the body [15] and is the most extensive and important mucosal surface of body. [18] The intestinal epithelium serves several crucial functions, exhibiting both innate and adaptive immune features.
In both instances an extensive length of small intestine was bypassed, not excised, excluding it from the alimentary stream. In both these variants a total of only about 45 cm (18 in) of normally absorptive small intestine was retained in the absorptive stream, compared with the normal length of approximately 7 metres (20 ft).
Unlike the gastric folds in the stomach, they are permanent, and are not obliterated when the intestine is distended.. The spaces between circular folds are smaller than the haustra of the colon, and, in contrast to haustra, circular folds reach around the whole circumference of the intestine.
During each mitosis, one of the two daughter cells remains in the crypt as a stem cell, while the other differentiates and migrates up the side of the crypt and eventually into the villus. These stem cells can differentiate into either an absorptive (enterocytes) or secretory (Goblet cells, Paneth cells, enteroendocrine cells) lineages. [3]
In human anatomy, the intestine (bowel or gut; Greek: éntera) is the segment of the gastrointestinal tract extending from the pyloric sphincter of the stomach to the anus and as in other mammals, consists of two segments: the small intestine and the large intestine.
The gut-associated lymphoid tissue lies throughout the intestine, covering an area of approximately 260–300 m 2. [5] In order to increase the surface area for absorption, the intestinal mucosa is made up of finger-like projections (), covered by a monolayer of epithelial cells, which separates the GALT from the lumen intestine and its contents.