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The last step in wet agglomeration is the final stabilization through drying. The agglomerated particles are dried to less than 5% water content, and cooled to below their glass transition temperature. [1] Wet agglomeration falls into two categories based on method of agitation: Mechanical mixing and pneumatic mixing.
The process can be very simple or very complex depending on the characteristics of the powders, the final objective of tablet making, and the equipment that is available. In the traditional wet granulation method the wet mass is forced through a sieve to produce wet granules which are subsequently dried.
Low shear wet granulation processes use very simple mixing equipment, and can take a considerable time to achieve a uniformly mixed state. High shear wet granulation processes use equipment that mixes the powder and liquid at a very fast rate, and thus speeds up the manufacturing process. Fluid bed granulation is a multiple-step wet granulation ...
Nowadays, to optimize the manufacturing process, particularly in wet granulation, various improved pieces of equipment which combines several processing steps (mixing, granulation and/or drying) are used. These are the mixer granulator and high shear mixing machine.
Respiratory virus season is officially here in the U.S., making it a prime time to catch a cold. And because the average adult gets two or three colds a year, you could be dealing with an ...
Pharmaceutical manufacturing is the process of industrial-scale synthesis of pharmaceutical drugs as part of the pharmaceutical industry. The process of drug manufacturing can be broken down into a series of unit operations , such as milling , granulation , coating , tablet pressing , and others.
“Research on age-related changes, including prevention of hair graying, is a long-term process. Identifying luteolin’s anti-graying effects may mark a step forward in anti-aging research.
Valentine’s Day is just around the corner, and if you’re searching for the best Valentine’s day chocolates for your special someone, we’re here to help.