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  2. Sarilumab - Wikipedia

    en.wikipedia.org/wiki/Sarilumab

    Sarilumab, sold under the brand name Kevzara, is a human monoclonal antibody medication against the interleukin-6 receptor. [6] Regeneron Pharmaceuticals and Sanofi developed the drug for the treatment of rheumatoid arthritis (RA), for which it received US FDA approval on 22 May 2017 and European Medicines Agency approval on 23 June 2017.

  3. Paclitaxel - Wikipedia

    en.wikipedia.org/wiki/Paclitaxel

    Paclitaxel, sold under the brand name Taxol among others, is a chemotherapy medication used to treat ovarian cancer, esophageal cancer, breast cancer, lung cancer, Kaposi's sarcoma, cervical cancer, and pancreatic cancer. [11]

  4. Protein-bound paclitaxel - Wikipedia

    en.wikipedia.org/wiki/Protein-bound_paclitaxel

    In 2014, Abraxane's sales were $848 million, 31 percent year-over-year increase. [18] The UK's National Institute for Health and Care Excellence (NICE) announced in 2015, that it would not support the routine use of protein-bound paclitaxel in advanced pancreatic cancer on the NHS. [19] However, this decision was changed in September 2017. [20]

  5. Medication costs - Wikipedia

    en.wikipedia.org/wiki/Medication_costs

    Medication costs can be the selling price from the manufacturer, that price together with shipping, the wholesale price, the retail price, and the dispensed price. [3]The dispensed price or prescription cost is defined as a cost which the patient has to pay to get medicines or treatments which are written as directions on prescription by a prescribers. [4]

  6. Prescription drug prices in the United States - Wikipedia

    en.wikipedia.org/wiki/Prescription_drug_prices...

    Within the year of 2014, the cost of prescriptions had increased by at least 11.4% and 58% within the last eight years. The average cost for a month supply of brand-name drugs can run up to a couple of hundred US dollars, whereas in Canada and Great Britain the same medication could cost up to $40 US dollars.

  7. These prices could climb within days if Trump slaps tariffs ...

    www.aol.com/prices-could-climb-within-days...

    That seasonal price impact could add another 30 cents per gallon, putting the total increase in gasoline prices at $1 per gallon if the tariffs remain in place at the onset of spring, Fitzgerald said.

  8. Mitotic inhibitor - Wikipedia

    en.wikipedia.org/wiki/Mitotic_inhibitor

    Similarly replacement of the acetyl group at C-16 with L-trp-OC 2 H 5, d-Ala(P)-(OC 2 H 5) 2, L-Ala(P)-(OC 2 H 5) 2 and I-Vla(P)-(OC 2 H 5) 2 gave rise to new analogues having anti- tubulin activity. Also it was found that the vindoline's indole methyl group is a useful position to functionalize potentially and develop new, potent vinblastine ...

  9. DHA-paclitaxel - Wikipedia

    en.wikipedia.org/wiki/DHA-paclitaxel

    DHA-paclitaxel (or Taxoprexin) is an investigational drug (from Protarga Inc) made by linking paclitaxel to docosahexaenoic acid (DHA), a fatty acid that is easily taken up by tumor cells; the DHA-paclitaxel “appears not to be cytotoxic until the bond with DHA is cleaved within the cell.” [1] The advantage of DHA-paclitaxel over paclitaxel is DHA-paclitaxel's ability to carry much higher ...

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