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Damage to the nerves that travel from the spinal cord to the bladder (peripheral nerves) can cause neurogenic bladder, usually the flaccid type. Nerve damage can be caused by diabetes, alcoholism, vitamin B12 deficiency, or genital herpes. Peripheral nerves can also be damaged as a complication of major surgery of the pelvis, such as for ...
Bladder sphincter dyssynergia (also known as detrusor sphincter dyssynergia (DSD) (the ICS standard terminology agreed 1998) [1] and neurogenic detrusor overactivity (NDO)) is a consequence of a neurological pathology such as spinal injury [2] or multiple sclerosis [3] which disrupts central nervous system regulation of the micturition (urination) reflex resulting in dyscoordination of the ...
Autonomic neuropathy (AN or AAN) is a form of polyneuropathy that affects the non-voluntary, non-sensory nervous system (i.e., the autonomic nervous system), affecting mostly the internal organs such as the bladder muscles, the cardiovascular system, the digestive tract, and the genital organs. These nerves are not under a person's conscious ...
The nerve roots from L4–S4 join in the sacral plexus which affects the sciatic nerve, which travels caudally (toward the feet). Compression, trauma or other damage to this region of the spinal canal can result in cauda equina syndrome. [citation needed] The symptoms may also appear as a temporary side-effect of a sacral extra-dural injection. [9]
Three spinal nerves in the sacrum (S2–4), commonly referred to as the pelvic splanchnic nerves, also act as parasympathetic nerves. Owing to its location, the parasympathetic system is commonly referred to as having "craniosacral outflow", which stands in contrast to the sympathetic nervous system, which is said to have "thoracolumbar outflow".
The pelvic splanchnic nerves are featured as a key plot point in "Parasites Lost", a 2001 episode of the American animated TV comedy Futurama; when protagonist Philip J. Fry is infected with parasitic worms, the rest of the crew use micro-droids to enter his body with the intention of tickling the pelvic splanchnic ganglion to trigger a convulsive bowel movement that they believe will expel ...
The parasympathetic nerve supply comes from the parasympathetic preganglionic neurons in the sacral spinal cord and also terminates in the longitudinal and circular smooth muscle layers. Finally the somatic nerve supply arises from the urethral sphincter motor neurons in the ventral horn of the sacral spinal cord; better known as Onuf's nucleus.
The pudendal nerve is a mixed nerve which contains motor (controlling muscles), sensory and sympathetic autonomic axons (nerve fibers). It stems from the ventral rami of the sacral spinal nerves S2, S3, and S4 of the sacral plexus. [33] [34] The path of the pudendal nerve is very complicated. [10] It passes through the pelvis, buttocks, and ...