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Lumbar puncture helps identify leukemic cells in the cerebrospinal fluid (CSF). [3] Even if leukemic cells are not found in the CSF at the time of diagnosis, it is highly likely that they will spread there over time. Thus, prophylactic intrathecal chemotherapy, a treatment to lower the risk of leukemia spreading to the spinal cord and brain by ...
Acute lymphoblastic leukemia (ALL) is a cancer of the lymphoid line of blood cells characterized by the development of large numbers of immature lymphocytes. [1] Symptoms may include feeling tired, pale skin color, fever, easy bleeding or bruising, enlarged lymph nodes, or bone pain. [1]
Illustration depicting lumbar puncture (spinal tap) Spinal needles used in lumbar puncture Illustration depicting common positions for lumbar puncture procedure. The person is usually placed on their side (left more commonly than right). The patient bends the neck so the chin is close to the chest, hunches the back, and brings knees toward the ...
[4] [5] If lumbar puncture is performed this may show increased protein levels but no white blood cells. [1] [3] [4] Computed tomography scanning may be performed in the first instance; this may show low density white matter areas in the posterior lobes. [4] The diagnosis is typically made with magnetic resonance imaging of the brain.
CLL is the most common type of leukemia in the UK, accounting for 38% of all leukemia cases. Approximately 3,200 people were diagnosed with the disease in 2011. [91] In Western populations, subclinical "disease" can be identified in 3.5% of normal adults, [92] and in up to 8% of individuals over the age of 70. [93]
These blood cells are not fully developed and are called blasts or leukemia cells. [2] Symptoms may include bleeding and bruising, bone pain, fatigue, fever, and an increased risk of infections. [2] These symptoms occur due to a lack of normal blood cells. [2] Diagnosis is typically made by blood tests or bone marrow biopsy. [2]