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Following a single oral dose of sertraline, mean peak blood levels of sertraline occur between 4.5 and 8.4 hours. [5] Bioavailability is likely linear and dose-proportional over a dose range of 150 to 200 mg. [5] Concomitant intake of sertraline with food slightly increases sertraline peak levels and total exposure. [5]
The recommended maximum daily dose of citalopram and escitalopram was reduced due to concerns with QT prolongation. [92] [93] [94] In overdose, fluoxetine has been reported to cause sinus tachycardia, myocardial infarction, junctional rhythms, and trigeminy.
Single doses of 50 to 200 mg sertraline have been found to result in peak plasma concentrations of 20 to 55 ng/mL (65–180 nM), [15] while chronic treatment with 200 mg/day sertraline, the maximum recommended dosage, has been found to result in maximal plasma levels of 118 to 166 ng/mL (385–542 nM). [16]
Common SSRIs include Prozac (fluoxetine), Zoloft (sertraline) and Lexapro (escitalopram). Effectiveness and side effect rates can vary between SSRIs. Effectiveness and side effect rates can vary ...
Sertraline (Zoloft) As an SSRI antidepressant, escitalopram is commonly prescribed to treat depression. The FDA also approves it for the treatment of generalized anxiety disorder (GAD).
This is a complete list of clinically approved prescription antidepressants throughout the world, as well as clinically approved prescription drugs used to augment antidepressants or mood stabilizers, by pharmacological and/or structural classification.